"There are other factors that meant he was in a situation with incurable, unbearable suffering.
There are eight dioceses, including one archdiocese, seat of the archiepiscopal residence and St.
Distelmans accepted on the grounds of 'unbearable psychological suffering'.
"The choice of Nathan Verhelst has nothing to do with fatigue of life," said Dr Distelmans.
After the civil ceremony, which must take place at a registry office, couples often have a religious or secular ceremony as part of their celebration but this is not required.
Mr Verhelst had hormone therapy in 2009, followed by a mastectomy and surgery to construct a penis in 2012. "I was ready to celebrate my new birth," he told the newspaper.
"But when I looked in the mirror, I was disgusted with myself. " The case will revive Belgium's debate over medical euthanasia as statistics show a steep year on year increase in the number of patients killed by doctors after a request to die.
The archbishop of Mechelen is ex officio the Great Chancellor of the university.
It was founded by the bishops of Belgium in 1834 to replace the Old University of Leuven, which the French Republic had suppressed in 1797.